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Ovarian Kaleidoscope Database (OKdb)

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glycosylphosphatidylinositol specific phospholipase D1 OKDB#: 5825
 Symbols: GPLD1 Species: human
 Synonyms: PLD, GPIPLD, PIGPLD, GPIPLDM, PIGPLD1  Locus: 6p22.3 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment NCBI Summary: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]
General function Enzyme
Comment
Cellular localization Secreted, Plasma membrane
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Oocyte, Granulosa
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
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created: July 15, 2020, 3:02 p.m. by: system   email:
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last update: July 15, 2020, 3:04 p.m. by: hsueh    email:



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