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Ovarian Kaleidoscope Database (OKdb)

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oviductal glycoprotein 1, 120kDa OKDB#: 5125
 Symbols: OVGP1 Species: human
 Synonyms: EGP, OGP, MUC9, CHIT5  Locus: 1p13 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment NCBI Summary: This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]
General function Extracellular binding protein
Comment
Cellular localization Secreted
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Oocyte
Comment highly expressed in the ovary based on Protein Atlas.
Follicle stages Preovulatory
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
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created: Feb. 2, 2015, 4:55 a.m. by: system   email:
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last update: Feb. 2, 2015, 4:56 a.m. by: hsueh    email:



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