| baculoviral IAP repeat containing 7 | OKDB#: 4762 |
| Symbols: | BIRC7 | Species: | human | ||
| Synonyms: | KIAP, LIVIN, MLIAP, RNF50, ML-IAP, | Locus: | 20q13.3 in Homo sapiens |
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| General Comment | NCBI Summary: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008] | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Aug. 21, 2012, 4:10 p.m. | by: |
hsueh email:
home page: |
| last update: | Aug. 21, 2012, 4:10 p.m. | by: | hsueh email: |
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