|nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2||OKDB#: 4294|
|Synonyms:||NFAT1, NFATP,MTND1,MTND1,||Locus:||20q13.2-q13.3 in Homo sapiens|
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R-L INTERACTIONS MGI
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|General Comment||NCBI Summary: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Expression regulated by|
|Genomic Region||show genomic region|
|Phenotypes and GWAS||show phenotypes and GWAS|
|created:||May 12, 2010, 1:17 p.m.||by:||
|last update:||May 13, 2010, 2 p.m.||by:||hsueh email:|
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