| Integrin, Alpha-e | OKDB#: 4226 |
| Symbols: | ITGAE | Species: | human | ||
| Synonyms: | CD103, HUMINAE, MGC141996,CD103 ANTIGEN|HUMAN MUCOSAL LYMPHOCYTE ANTIGEN 1, ALPHA SUBUNIT | Locus: | 17p13 in Homo sapiens |
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| General Comment | NCBI Summary: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq] | ||||
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| Ovarian localization | Oocyte | ||||
| Comment | zyxw | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Feb. 20, 2010, 7:05 p.m. | by: |
hsueh email:
home page: |
| last update: | Feb. 20, 2010, 7:06 p.m. | by: | hsueh email: |
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