| Nucleoporin, 88-kd | OKDB#: 3628 |
| Symbols: | NUP88 | Species: | human | ||
| Synonyms: | MGC8530, | Locus: | 17p13.2 in Homo sapiens |
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| General Comment | NCBI Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. | ||||
| General function | Intracellular protein transport, Channel/transport protein | ||||
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| Cellular localization | Nuclear | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
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| created: | Oct. 30, 2006, 4:34 p.m. | by: |
amazinmazin email:
home page: |
| last update: | Oct. 30, 2006, 4:34 p.m. | by: | amazinmazin email: |
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