| chromatin licensing and DNA replication factor 1 | OKDB#: 3595 |
| Symbols: | CDT1 | Species: | human | ||
| Synonyms: | DUP, RIS2 | Locus: | 16q24.3 in Homo sapiens |
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For retrieval of Nucleotide and Amino Acid sequences please go to:
OMIM
Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles new! Amazonia (transcriptome data) new! R-L INTERACTIONS MGI |
| General Comment | NCBI Summary: The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011] | ||||
| General function | Cell death/survival, DNA Replication, DNA binding | ||||
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| Cellular localization | Nuclear | ||||
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| Ovarian localization | Oocyte | ||||
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| Mutations | 0 mutations | ||||
| Genomic Region | show genomic region | ||||
| Phenotypes and GWAS | show phenotypes and GWAS | ||||
| Links |
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| created: | Oct. 9, 2006, 3:51 p.m. | by: |
amazinmazin email:
home page: |
| last update: | April 22, 2015, 7:31 a.m. | by: | hsueh email: |
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