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Hsueh lab

HPMR

Polyadenylate-binding Protein-interacting Protein 1</title><base Target=_top></head><body Bgcolor=#f

OKDB#: 3345

	Symbols:	symbols		Species:	human
	Synonyms:	MGC12360,POLY(A)-BINDING PROTEIN-INTERACTING PROTEIN 1, PAIP1\|PABC1-INTERACTING PROTEIN 1		Locus:	5p12 in Homo sapiens

For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
Mammalian Reproductive Genetics Endometrium Database Resource Orthologous Genes UCSC Genome Browser GEO Profiles ^new! Amazonia (transcriptome data) ^new!
R-L INTERACTIONS MGI

General Comment

NCBI Summary: The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

General function

RNA binding, Translation factor

Comment

Cellular localization

Cytoplasmic

Comment

Ovarian function

Oogenesis, Oocyte maturation

Comment

Gene whose expression is detected by cDNA array hybridization: cell surface antigens, cell adhesion, receptors Rozenn Dalbis-Tran and Pascal Mermilloda

Expression regulated by

Comment

Ovarian localization

Comment

Follicle stages

Comment

Phenotypes

Mutations

0 mutations

Genomic Region

show genomic region

Phenotypes and GWAS

show phenotypes and GWAS

Links

OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways

Recent Publications

None

Search for Antibody

created:

July 18, 2006, 10:47 a.m.

by:

alex email:
home page:

last update:

July 26, 2006, 2:38 p.m.

by:

Alex email:

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