NCBI Summary:
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]
General function
Nucleic acid binding, DNA binding, Transcription factor
Comment
Cellular localization
Nuclear
Comment
Ovarian function
Oogenesis, Oocyte maturation
Comment
Gene whose expression is detected by cDNA array hybridization: cell surface antigens, cell adhesion, receptors. Also, relative transcript level reproducibly increases during IVM Rozenn Dalbi?Tran and Pascal Mermilloda