NCBI Summary:
The protein encoded by this gene is a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is found to be involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation. Alternatively spliced transcript variants encoding distinct isoforms have been reported.