tetraspanin 3 | OKDB#: 3128 |
Symbols: | TSPAN3 | Species: | human | ||
Synonyms: | TM4-A, TM4SF8, TSPAN-3, | Locus: | 15q24.3 in Homo sapiens | HPMR |
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Entrez Gene
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General Comment | NCBI Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described. | |||
General function | Receptor | |||
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Cellular localization | Plasma membrane | |||
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Ovarian function | ||||
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Expression regulated by | ||||
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Ovarian localization | Cumulus | |||
Comment | The human cumulus-oocyte complex gene-expression profile. Assou S et al. BACKGROUND: The understanding of the mechanisms regulating human oocyte maturation is still rudimentary. We have identified transcripts differentially expressed between immature and mature oocytes and cumulus cells. | |||
Follicle stages | ||||
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Phenotypes | ||||
Mutations | 0 mutations | |||
Genomic Region | show genomic region | |||
Phenotypes and GWAS | show phenotypes and GWAS | |||
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created: | June 20, 2006, 1:11 p.m. | by: |
Alex email:
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last update: | June 20, 2006, 3:58 p.m. | by: | hsueh email: |
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