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Ovarian Kaleidoscope Database (OKdb)

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Hsueh lab

HPMR

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since 01/2001:
176557

Macrophage Mannose Receptor OKDB#: 2197
 Symbols: MRC1 Species: human
 Synonyms:  Locus: 10p13 in Homo sapiens
HPMR


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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link to BioGPS
General Comment NCBI Summary: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
General function Receptor
Comment
Cellular localization Plasma membrane
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization
Comment This gene was found in a mouse DNA array analysis of transcripts expressed in mouse preovulatory follicles.
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways
Recent Publications
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created: Oct. 14, 2003, 12:10 p.m. by: xin   email:
home page:
last update: March 28, 2004, 4:12 p.m. by: system    email:



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