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Ovarian Kaleidoscope Database (OKdb)

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HPMR

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interleukin 10 receptor, beta OKDB#: 2190
 Symbols: IL10RB Species: human
 Synonyms: CRFB4, CRF2-4, D21S58, D21S66, CDW210B, IL-10R2  Locus: 21q22.11 in Homo sapiens
HPMR


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment This gene was found in a mouse DNA array analysis of transcripts expressed in mouse preovulatory follicles. Goes up during follicle development.

NCBI Summary: The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]
General function Receptor
Comment
Cellular localization Plasma membrane
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Oocyte
Comment zyxw
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
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created: Oct. 14, 2003, 11:38 a.m. by: xin   email:
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last update: Nov. 16, 2015, 2:56 p.m. by: hsueh    email:



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