| OHX; oocyte specific homeobox gene | OKDB#: 1642 |
| Symbols: | OHX; oocyte specific homeobox gene | Species: | mouse | ||
| Synonyms: | Locus: |
|
For retrieval of Nucleotide and Amino Acid sequences please go to:
UCSC Genome Browser
GEO Profiles
new!
Amazonia (transcriptome data)
new!
R-L INTERACTIONS MGI |
| General Comment |
Yeh YJ, et al reported that Ohx is a homeobox-encoding gene preferentially expressed in
mature oocytes.
There is abundant evidence to indicate that the homeobox genes are
developmentally important. We used the NCBI dbEST databases of early mouse
embryos to identify novel homcobox-containing sequence tags. Ohx
(oocyte-specific homeobox gene) was one of several genes identified by in
silico cloning. The full-length Ohx cDNA was cloned and its genomic
organization was characterized. The Ohx gene spans 1.6 kb, encodes three exons
and maps to the proximal region of mouse chromosome 7. Reverse transcriptase
polymerase chain reaction analyses show that Ohx is preferentially expressed
in one- and two-cell embryonic stages, as well as in the ovary. Whole mount in
situ hybridization analysis demonstrates that the Ohx mRNA was exclusively
localized to the oocytes of the mature ovary. Ohx is one of the few
homeobox-encoding genes preferentially expressed during mammalian oogenesis.
|
|||
| General function | DNA binding, Transcription factor | |||
| Comment | ||||
| Cellular localization | Nuclear | |||
| Comment | ||||
| Ovarian function | Oogenesis | |||
| Comment | ||||
| Expression regulated by | ||||
| Comment | ||||
| Ovarian localization | Oocyte | |||
| Comment | ||||
| Follicle stages | ||||
| Comment | ||||
| Phenotypes | ||||
| Mutations | 0 mutations | |||
| Genomic Region | show genomic region | |||
| Phenotypes and GWAS | show phenotypes and GWAS | |||
| Links |
|
| created: | Nov. 5, 2002, 6:20 a.m. | by: |
hsueh email:
home page: |
| last update: | Nov. 5, 2002, 6:20 a.m. | by: | system email: |
Click here to return to gene search form